If your Computer has a 64-bit processor and supports Intel VT-X or AMD-v virtualization, which is available in most modern CPUs, then Windows 10 offers extra virtualization-based security features.
One of these features is called Core Isolation, which uses hardware virtualization to isolate critical parts of the operating system’s kernel from user-mode drivers and software running on the PC. When enabled, this prevents malware or exploits from gaining access to the secure kernel to bypass security controls, inject malware, or perform other malicious behavior.
A subset of the Core Isolation feature is a feature called ‘Memory Integrity‘, which protects memory from being injected with malicious code by malware or malicious attacks.
Memory Integrity may block drivers
When enabled, this feature locks down the computer and may cause drivers to not operate properly or even load.
When the driver is not loaded properly, Windows will log an error that states “A driver can’t load on this device”, which could lead to issues ranging from harmless to severe depending on the driver.
In situations like this, Microsoft recommends that you check for an updated driver that may have fixed the issue causing it to be blocked.
If that does not help, you can disable the Memory Integrity security feature so that the driver can load.
To disable Memory Integrity, please follow these steps: See this article Below